Sigrid Therapeutics Receives Notice of Allowance for US Patent Covering Novel Porous Silica Materials

Sigrid Therapeutics receives US patent approval for SiPore® technology

Stockholm, 8 September 2025 – Sigrid Therapeutics announces that the United States Patent and Trademark Office, USPTO, has issued a Notice of Allowance for the company's patent application US2022135411A1, “Highly Structured Porous Silica Materials and Biological Uses Thereof”. This is an important step in the company's patent strategy and strengthens its position in next-generation health technology based on porous silicon.

The patent covers new porous silica particles with a hierarchical pore structure, the foundation of Sigrid's SiPore® platform. Unlike conventional silica, SiPore® is engineered with precisely controlled pores that can trap digestive enzymes in the gut. This physical mechanism opens the way for clinically proven, non-systemic solutions for blood sugar regulation, weight management and broader metabolic health, among other things.

– This confirms the strength of our scientific innovation and unique technology. The US is a key market and this patent strengthens our commercial position and ability to deliver new solutions to some of the greatest health challenges of our time, says Ghislaine Robert-Nicoud, Head of Product Development at Sigrid Therapeutics.

The patent is expected to be formally granted once the administrative steps are completed and strengthens Sigrid's already extensive patent portfolio. The company already holds two US patents (US 10,695,294 and US 12,121,612) and European patent EP2916852B1, validated in the EU, the United Kingdom, Switzerland, Norway, Iceland and Turkey, among others, as well as granted patents in Canada, Australia, Japan and Israel.

About Sigrid Therapeutics
Sigrid is a Swedish company developing SiPore®, a 100% natural mineral technology that acts locally in the gut by mechanically trapping digestive enzymes. This slows down the breakdown of carbohydrates and fat, reduces calorie uptake and helps to stabilise blood sugar, support healthy weight management and promote metabolic balance – without entering the bloodstream or causing systemic side effects.

The product portfolio includes:
• Carb Fence™ – medical nutrition for the dietary management of impaired glucose tolerance, under medical supervision.
• Glucose Stabiliser – a daily dietary supplement for long-term metabolic health.

Source: Sigrid Therapeutics' website.

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